Estradiol
Definition
Estradiol: Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
Other Entries
17 beta-Estradiol
Estradiol-17 beta
Oestradiol
17 beta-Oestradiol
Aerodiol
Estrace
Estraderm TTS
Estradiol Hemihydrate
Estradiol Hemihydrate, (17 alpha)-Isomer
Estradiol Monohydrate
Estradiol, (+-)-Isomer
Estradiol, (-)-Isomer
Estradiol, (16 alpha,17 alpha)-Isomer
Estradiol, (16 alpha,17 beta)-Isomer
Estradiol, (17-alpha)-Isomer
Estradiol, (8 alpha,17 beta)-(+-)-Isomer
Estradiol, (8 alpha,17 beta)-Isomer
Estradiol, (9 beta,17 alpha)-Isomer
Estradiol, (9 beta,17 beta)-Isomer
Estradiol, Monosodium Salt
Estradiol, Sodium Salt
Estradiol-17 alpha
Estradiol-17beta
Novartis Pharmaceuticals Brand of Estradiol
Orion Brand of Estradiol
Ovocyclin
Vivelle
17 beta Estradiol
17 beta Oestradiol
Estradiol 17 alpha
Estradiol 17 beta
Estradiol 17beta
Estradiol Orion Brand
Pharmacy Actions
Allowable Qualifiers
administration & dosage adverse effects agonists analogs & derivatives analysis biosynthesis blood cerebrospinal fluid chemical synthesis chemistry classification contraindications deficiency diagnostic use economics genetics history immunology isolation & purification metabolism pharmacokinetics pharmacology physiology poisoning radiation effects secretion standards supply & distribution therapeutic use toxicity urine
Categories
Entry Date
01-01-1999
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Diabetes Supplies | Diabetic Groups
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Free Diabetes Supplies
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
